Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis
Chen, ZY; Li, JP; Wei, LW; Xu, WX; Shi, Y
2011
Source PublicationEXPERT SYSTEMS WITH APPLICATIONS
ISSN0957-4174
Volume38Issue:10Pages:9,12151-12159
AbstractGene expression profiling using DNA microarray technique has been shown as a promising tool to improve the diagnosis and treatment of cancer. Recently, many computational methods have been used to discover maker genes, make class prediction and class discovery based on gene expression data of cancer tissue. However, those techniques fall short on some critical areas. These included (a) interpretation of the solution and extracted knowledge. (b) Integrating various sources data and incorporating the prior knowledge into the system. (c) Giving a global understanding of biological complex systems by a complete knowledge discovery framework. This paper proposes a multiple-kernel SVM based data mining system. Multiple tasks, including feature selection, data fusion, class prediction, decision rule extraction, associated rule extraction and subclass discovery, are incorporated in an integrated framework. ALL-AML Leukemia dataset is used to demonstrate the performance of this system. (C) 2011 Elsevier Ltd. All rights reserved.
KeywordSupport Vector Machine Multiple-kernel Learning Feature Selection Data Fusion Decision Rule Associated Rule Subclass Discovery Gene Expression
Subject AreaComputer Science ; Artificial Intelligence ; Electrical & Electronic ; Engineering ; Operations Research & Management Science
Indexed BySCI
Language英语
WOS IDWOS:000292169500017
Citation statistics
Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.casisd.cn/handle/190111/4267
Collection中国科学院科技政策与管理科学研究所(1985年6月-2015年12月)
Recommended Citation
GB/T 7714
Chen, ZY,Li, JP,Wei, LW,et al. Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis[J]. EXPERT SYSTEMS WITH APPLICATIONS,2011,38(10):9,12151-12159.
APA Chen, ZY,Li, JP,Wei, LW,Xu, WX,&Shi, Y.(2011).Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis.EXPERT SYSTEMS WITH APPLICATIONS,38(10),9,12151-12159.
MLA Chen, ZY,et al."Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis".EXPERT SYSTEMS WITH APPLICATIONS 38.10(2011):9,12151-12159.
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