Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis

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	Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis
	Chen, ZY; Li, JP; Wei, LW; Xu, WX; Shi, Y
发表期刊	EXPERT SYSTEMS WITH APPLICATIONS
关键词	Support Vector Machine Multiple-kernel Learning Feature Selection Data Fusion Decision Rule Associated Rule Subclass Discovery Gene Expression
摘要	Gene expression profiling using DNA microarray technique has been shown as a promising tool to improve the diagnosis and treatment of cancer. Recently, many computational methods have been used to discover maker genes, make class prediction and class discovery based on gene expression data of cancer tissue. However, those techniques fall short on some critical areas. These included (a) interpretation of the solution and extracted knowledge. (b) Integrating various sources data and incorporating the prior knowledge into the system. (c) Giving a global understanding of biological complex systems by a complete knowledge discovery framework. This paper proposes a multiple-kernel SVM based data mining system. Multiple tasks, including feature selection, data fusion, class prediction, decision rule extraction, associated rule extraction and subclass discovery, are incorporated in an integrated framework. ALL-AML Leukemia dataset is used to demonstrate the performance of this system. (C) 2011 Elsevier Ltd. All rights reserved.
	2011
卷号	38 期号:10 页码:9,12151-12159
ISSN	0957-4174
学科领域	Computer Science ; Artificial Intelligence ; Electrical & Electronic ; Engineering ; Operations Research & Management Science
收录类别	SCI
语种	英语
WOS记录号	WOS:000292169500017
引用统计	被引频次：22[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.casisd.cn/handle/190111/4267
专题	中国科学院科技政策与管理科学研究所(1985年6月-2015年12月)
推荐引用方式 GB/T 7714	Chen, ZY,Li, JP,Wei, LW,et al. Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis[J]. EXPERT SYSTEMS WITH APPLICATIONS,2011,38(10):9,12151-12159.
APA	Chen, ZY,Li, JP,Wei, LW,Xu, WX,&Shi, Y.(2011).Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis.EXPERT SYSTEMS WITH APPLICATIONS,38(10),9,12151-12159.
MLA	Chen, ZY,et al."Multiple-kernel SVM based multiple-task oriented data mining system for gene expression data analysis".EXPERT SYSTEMS WITH APPLICATIONS 38.10(2011):9,12151-12159.

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